Knowing the person is deemed requisite to establishing a professional relationship and guide clinical decision-making in nursing practice. Knowing entails appreciating complexities of an individual within the context of interrelated phenomena that influence healing and health, such as biological, psychosocial and environmental aspects of a person’s wholeness. Currently little is understood about knowing the person through use of telehealth technology. The purpose of this study is to determine how nurses come to know the person through use of remote patient monitoring (RPM) technology and my goal is to arrive at a theoretical conceptualization of basic social processes associated with the nurse coming to know the person in delivery of care through RPM. A qualitative research design based on a constructivist approach to grounded theory (Charmaz, 2010) will be used to guide this study. To facilitate achievement of theoretical sufficiency, I will recruit 20 - 25 participants from several agencies in Ontario and New Brunswick, Canada that provide RPM services. Eligible participants are primarily registered nurses (RN) who use RPM in delivery of care. Data sources will primarily be interviews with RNs but also include other sources such as observation of RNs using RPM, clinical guidelines, education modules and policy documents. Analysis techniques of constant comparison, coding and memo writing for theory development consistent with Charmaz’s grounded theory approach will be used for analysis and development of a substantive theory. This study will provide insight into how nurses come to know the person through RPM, as well as requisite skills, knowledge, and attributes for RNs to know the person when using this modality of telehealth technology. This knowledge will inform standard of nursing practice in the provision of appropriate, safe and holistic nursing care articulated by professional nursing bodies, such as the College of Nurses of Ontario and Canadian Nurses Association.