The purpose of this research was (1) to identify direction in creating value-add product and service of ethnic group entrepreneurs and (2) to analyze the success of ethnic group entrepreneurs in Maehongson province. It was participatory action research. The population was 7 ethnic groups of entrepreneurs, i.e. Tai Yai, Yunan, Hmong, Lisu, Lahu, Lawa and Karen. The research tool consisted of interview, meeting, seminar and conference. The data analysis was carried out on three dimensions for the difference of data on time, location and subject content with full participation from all relevant parties. The outcomes of research revealed that ethnic group entrepreneurs had applied local wisdom, culture, tradition, belief and way of life through innovation and creativity in creating value-add of ethnic products. They focused on quality standard, legend or story on packaging for differentiation and uniqueness. The success of ethnic entrepreneurs was the outcomes of wisdom inheritance from ancestor on craftsmanship skill, determination, accountability, product creativity with modern innovation on continuous basis and self sufficiency.